Related Items:commisioner james smith, re-deployment Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 04 Feb 2016 – The fire at HJ Robinson may have been intentionally set; but still no one is saying officially and the Police Commissioner on Monday told the National Security Council that he does not believe the movement of officers out of Grand Turk and into Provo was the reason the fire was able to be set. The Commissioner noted that there remained 38 police officers in Grand Turk and advised that, “It was important that recent, unrelated incidents should not be viewed as part of a wider pattern.” Commissioner James Smith was referencing the turf wars, vandalism, break in spree and now the alleged arson – all taking place in Grand Turk. The Commissioner assured the Governor, the Premier, the Border Control Minister and the Attorney General that crimes were down in Provo during Christmas, when compared to 2014 statistics of the same period.
KUSI Newsroom, Posted: April 9, 2018 SAN DIEGO (KUSI) — The San Diego City Council’s Select Committee on Homelessness voted Monday to instruct staff to create a pilot program to better connect homeless people with job opportunities.Staff will explore how the city can use its rapid re-housing programs to connect people with long-term employment. The re-housing programs connect families experiencing homelessness to permanent housing through a package of assistance that includes temporary financial assistance, counseling and educational services.The pilot program will likely involve at least 100 families currently being served by re-housing programs to determine the impact that employment-focused assistance can have on the homeless.Those families would be provided with long-term employment support to assist them in landing jobs and ensure their long-term success in those positions.Recommendations and details of the pilot will be worked out in the coming weeks by staff and sent to the committee for consideration in June.The program seeks to address relatively poor performance by San Diego re-housing programs compared to other cities.Over the last two years, 54 percent of San Diego re-housing clients exiting the program went into a permanent housing situation, compared to 73 percent of those in Los Angeles, according to a city staff report.Nearly 25 percent of clients aged 18-62 entering the San Diego programs in 2017 reported income from employment. The percentage of people earning employment income grew by just one percentage point after exiting the program that same year, according to the report.“What that’s telling us is we’re probably not doing a great job with actually getting people jobs,” consultant Kris Kuntz said.A more robust focus on employment could improve those numbers, homelessness advocates and city staff said.“Our homeless system and our rapid re-housing program are working very hard to get people jobs out there,” Kuntz said. But “we want to start doing the rapid re-housing model better here, not just in the city, but in the San Diego region.City staff will look at Denver as one example of a successful program, in which 39 percent of participants found full-time work. San Diego City Council votes to create pilot program to connect homeless people with job opportunities April 9, 2018 Categories: Local San Diego News FacebookTwitter KUSI Newsroom Updated: 12:00 PM
More information: Xiaofeng Huang et al. An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells, Nature Communications (2017). DOI: 10.1038/ncomms14751AbstractInfluenza virus utilizes host splicing machinery to process viral mRNAs expressed from both M and NS segments. Through genetic analysis and functional characterization, we here show that the NS segment of H7N9 virus contains a unique G540A substitution, located within a previously undefined exonic splicing enhancer (ESE) motif present in the NEP mRNA of influenza A viruses. G540A supports virus replication in mammalian cells while retaining replication ability in avian cells. Host splicing regulator, SF2, interacts with this ESE to regulate splicing of NEP/NS1 mRNA and G540A substitution affects SF2–ESE interaction. The NS1 protein directly interacts with SF2 in the nucleus and modulates splicing of NS mRNAs during virus replication. We demonstrate that splicing of NEP/NS1 mRNA is regulated through a cis NEP-ESE motif and suggest a unique NEP-ESE may contribute to provide H7N9 virus with the ability to both circulate efficiently in avian hosts and replicate in mammalian cells. UN sees bird flu changes but calls risk of people spread low Explore further Influenza A (H7N9) as viewed through an electron microscope. Both filaments and spheres are observed in this photo. Credit: CDC (Phys.org)—A team of researchers affiliated with several institutions in Hong Kong and mainland China has isolated a change in a single nucleotide that is responsible for allowing the H7N9 flu virus to replicate in both birds and humans. In their paper published in the journal Nature Communications, the team describes their efforts in searching for the factors involved when avian flu jumps to humans and what their findings could mean for reducing the spread of future flu epidemics. Journal information: Nature Communications This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2017 Phys.org Citation: Single nucleotide change responsible for allowing H7N9 flu to jump from birds to humans found (2017, March 23) retrieved 18 August 2019 from https://phys.org/news/2017-03-nucleotide-responsible-h7n9-flu-birds.html Scientists around the world are very concerned about how viruses spread from animals to humans—the fear is that one day, a super-virus may emerge, one that is both easily transmissible and deadly, potentially killing millions of people around the globe. In this new effort, the researchers focused on H7N9, a flu virus that was first found to jump from birds (mainly chickens) to humans as recently as 2000. It has infected people mostly in China, but its recent history offered an opportunity to learn more about how a virus jumps to humans.To learn more about the virus, the researchers obtained samples and subjected them to genetic analysis looking for any differences between them and other avian flu viruses that do not spread to humans. They found a unique nucleotide (an RNA building block) substitution called NS-G540A in the NS segment—a mutation that allowed the virus to replicate in both avian and human (and other mammalian) hosts. They report that they found the mutation on some other flu variants as well, such as H9N2.The researchers note that in addition to learning more about how a virus can make the leap between species, the identification of the nucleotide also offers the medical community a biomarker—testing chickens and other fowl infected with a flu variant for the marker would allow for identifying birds carrying a flu variant that can cause infections in the people that handle them. They note also that they found no evidence that the mutation played a role in allowing the virus to spread between humans once it made the leap from an avian source.